Stem Cell Review: Mesenchymal Stem Cells and Connective Disorders (EP6)
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Stem Cell Review: Mesenchymal Stem Cells and Connective Disorders
Gordana Vunjak-Novakovic of Columbia University gives us an explanation of what mesenchymal stem cells are; adult stem cells that are present in many organs and tissues, and that drive tissue repair. The main sources of mesenchymal stem cells are bone marrow and fat (adipose tissue), although they can be found lesser quantities in muscle, blood, heart, liver, and other tissues. Mesenchymal stem cells can be used to regenerate many different types of tissue, but the most promising clinical applications are in bone, cartilage, ligaments, muscle, neural cells, and striated muscles. Mesenchymal stem cells are thought to repair the heart muscles through revascularization and recruitment of repair cells, but the data does not yet show that they can convert into heart muscle. In a future outlook, Gordana shares with us what she thinks is in the near future of mesenchymal stem cells: well defined cells that can be differentiated predictably, understanding the importance of cell origin on clinical outcome, new FDA friendly delivery routes, more effective functional markers and monitoring, and increasing interdisciplinary collaboration.
This is the Episode 6 of the Stem Cell Review, aired on November 12th, 2009
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Credits
In Order of Appearance:
GUESTS
Gordana Vunjak-Novakovic - Columbia University // Professor, Department of Biomedical Engineering, Columbia University, New York NY; Director, Laboratory for Stem Cells and Tissue Engineering; Professor of Biomedical Engineering in Surgery, College of Physicians and Surgeons, Columbia University, New York NY; Professor of Biomedical Engineering & Dental and Craniofacial Bioengineering (in Dentistry), College of Dental Medicine, Columbia University, New York NY; Adjunct Professor, Department of Biomedical Engineering, Tufts University, Medford MA; Visiting Scientist, Div. of Health Sciences and Technology, M.I.T., Cambridge MA
IMAGES
Stem Cell Review Studio Background Pictures provided by the California Institute of Regenerative Medicine
A Special Thanks to:
- Ferghana Partners Group
- ISSCR / The International Society for Stem Cell Research
- Genetics Policy Institute / World Stem Cell Summit
- Hilton Hotels / The Hilton Diagonal Mar in Barcelona
MUSIC
Protest by soundroll Five Tribes by ventilo35
Last but not Least!
- Freya Alugas
- Pat Becker
- Melissa Carpenter
- Ellen Charles
- Meagan Comerford
- Karena Essex
- Elisabet Fabregas
- Mario Fante
- Rocio Fontela
- Liz Freyn
- Don Gibbons
- Raj Kaur
- Paul Laland
- Gemma Llamas
- Jillian McFady
- Mary Lou McKeone
- Didier Montarras
- Mario Oliete
- Jose Maria Ruiz
- Valerie Tucker
- Kristen April Uekermann
- Nancy Witty
- Jessica Yingling
About
Acknowledgements
